Advanced Statistical Modeling

A two-part medical example about binary outcomes, p-values, and clustered data.
Author

Samer El Kababji

Logistic and Mixed-Effects Regression

This lesson follows the same fictional medical study from an ordinary logistic regression to a mixed-effects logistic regression. The outcome is whether a patient recovered within 30 days, and patients are grouped within clinics.

1. Logistic Regression and p-values

Fit a logistic regression, translate log-odds into odds ratios and probabilities, and interpret p-values without treating them as automatic decisions about clinical importance.

Prerequisites: basic algebra and introductory R.

2. Mixed-Effects Logistic Regression

Account for patients being grouped within clinics, interpret a random intercept, and compare the result with the ordinary logistic model.

Prerequisites: 1. Logistic Regression and p-values.